Year:2022   Volume: 4   Issue: 3   Area:

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  3. ID: 187

Alyaa Khider ABBAS

SYNTHESIS, SPECTROSCOPIC, THERMAL AND BIOLOGICAL STUDIES OF SOME NOVEL ‎METAL IONS COMPLEXES

In the current study, a novel heterocyclic azo ligand, 4-[6-(p-phenyl phenol)azo] ‎cytosine(PAC), is synthesized through a general diazo coupling reaction with lanthanide ions ‎‎[La(III), Nd(III), and Eu(III)]. The molecular formulae of the newly synthesized compounds ‎were established using a variety of spectroscopic methods, including [FT-IR, UV-Vis, and ‎HNMR], elemental analysis (C.H.N), thermal gravimetric analysis (TGA), magnetic ‎measurement, molar conductivity measurement, stability constant, and Gibbs free energy. ‎Using the mole ratio method, the complexes stoichiometry was determined using data from ‎spectroscopic analyses of the complexes' solutions for the chosen ions. The metal to ligand ‎mole ratio, however, was (1:2). When the biological effectiveness of each compound was ‎tested against various bacteria and fungi strains, the results showed good activity when ‎compared to the standard medication. additionally possess effective cancer prevention and ‎dyeing performance.‎

Keywords: Cytosine, Azo Dye, Cytotoxicity, Apoptosis

http://dx.doi.org/10.47832/2717-8234.12.33


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