IMMUNOLOGICAL STUDY OF HUMAN PAPILLOMAVIRUS ASSOCIATED WITH TRICHMONAS VAGINALIS INFECTIONS ISOLATED FROM WOMEN WITH CERVICITIS
A total of 100 samples were divided into 50 samples of infected patients and 50 as a control group. They were collected from women attended to Al- Elwea Hospetal for delivery during the period from March 2021 to February 2022. According to the results in our study, the mean and SD of patients (M±SD) was 34.82±11.004 compared to the control group (40.160±13.69), (SN). The Mean±SE of Papilloma IgM was (96.41±3.69) in comparison to the controls (19.14±1.009), with highly significant differences (P=0.001). The Mean±SE of pap IgG was (68.70±6.90) compared to the healthy controls (19.58±0.95) with (H.S). While the Trichomonas- IgM mean and SD was (1.53±0.19) compared to the control group (0.09±0.02) with (H.S). Also the Trichomonas- IgG Mean±SE was (9.56±1.22) compared to the healthy control (0.07±0.016) with (H.S), (P<0.001). The No. and rate of Papiloma-IgM was 19 (54.3%) , and with Trichmonas infections-IgG was 50 (100.0%), (S>N), (p=0.9). The No. and rate of Papiloma-IgG was 14 (36.8%), and with Trichmonas infections-IgM was 50 (100.0%) with a (S>N), (p=0.7). The No. and rate of Papiloma-IgG was 13 (37.1%) and in Trichmonas –IgG was 50 (100.0%) with significant diffrences (p=0.8). The Mean±SE of Tumor necrosis Factor (TGF) was (97.93±4.07) compared to the control group (22.06±1.519) with (H.S), (P=0.001), while the Mean±SE of MPC-1 was (61.67±22.65) compared to the helthy control (15.83±0.43, (H.S), (P=0.04) and the Mean±SE of IL-10 was (4.42±0.16) compared to the healthy cases (4.37±0.15) with (N.S) while the Mean±SE of LTB-4was (94.24±4.03) compared to the control group (19.36±0.99) (H.S), (P<0.001). The purpose of this study to detct the association of Human Papillomavirus with Trichmonas vaginalis infections in women with Cervicitis
Keywords: Human Papillomavirus, Trichmonas, women, Cervicitis